It may seem incredulous, but breast tumors may have something in common with embryos … at least in mice, say researchers at The University of Texas MD Anderson Cancer Center.
NIBIB-supported researchers have created tiny gel particles that can perform the same essential functions as platelets. The particles could one day be used to control excessive bleeding following traumatic injury or in individuals with impaired clotting due to an inherited condition or as a result of certain medications or chemotherapy.
In a study published in Nature Medicine, UNC Lineberger Comprehensive Cancer Center researchers report their findings of just how a certain tumor-suppressing protein helps prevent colon cancer. With this discovery, researchers believe they’ve found a possible drug target for colon cancer patients who lack the tumor suppressor.
Male and female mice use different immune cells to process chronic pain, indicating that different therapies for different genders could better target the problem.
New research led by the University of Adelaide hopes to close the debate on whether a major mud volcano disaster in Indonesia was triggered by an earthquake or had man-made origins.
Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.
New research reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain, and the way we execute basic biomedical research using mice.
Physicists have found that intense visual input forces the brain into a brief moment of chaos, but the visual cortex spontaneously returns the brain to its optimal function.
A new technique pioneered at Brookhaven National Laboratory reveals atomic-scale changes during catalytic reactions in real time and under real operating conditions.
In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
This phenomenon generates like a tail or a head of hair giving it the appearance of a giant comet. Already observed in some very large and very hot exoplanets, this phenomenon is viewed for the first time with such a magnitude. The cloud might explain the formation of some hot and rocky super-Earths. It would also be an indicator for detecting extrasolar oceans. Finally, it would be used to envisage the future of our atmosphere. These results are published in the latest edition of the journal Nature.
A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer, potentially at a stage amenable to surgical treatment, according to a study at The University of Texas MD Anderson Cancer Center.
A progress article published June 23 in the journal Nature Materials describes recent developments and predicts future advances in phonon wave interference and thermal bandgap materials -- approaches to controlling heat transfer.
A progress article published June 23 in the journal Nature Materials describes recent developments and predicts future advances in phonon wave interference and thermal bandgap materials -- approaches to controlling heat transfer.
New technique developed by Brookhaven Lab scientists to rapidly create multi-layered, self-assembled grids could transform the manufacture of high-tech coatings for anti-reflective surfaces, improved solar cells, and touchscreen electronics.
Using optogenetics, researchers have established a new approach for pacing the heart and synchronizing its mechanical activity without a conventional electrical pacemaker. Could help avoid many drawbacks of electrical pacemakers.
In 1999 Danish scientist Per Bak made the startling proposal that the brain remained stable for much the same reason a sand pile does; many small avalanches hold it at a balance point, where --in the brain's case -- information processing is optimized. Now scientists have showed for the first time that a brain receiving and processing sensory input follows these dynamics.
The new study, co-led by Howard Hughes Medical Institute (HHMI) investigator David Reich at Harvard Medical School and Svante Pääbo at the Max Planck Institute in Germany, provides the first genetic evidence that humans interbred with Neanderthals in Europe.
Regenerative medicine researchers at UT Southwestern Medical Center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.
Scientists built nanoscale mirrors to trap light around atoms inside of diamond crystals. The mirrored cavities allow light to bounce back and forth up to 10,000 times, enhancing the normally weak interaction between light and the electronic spin states in the atoms. As a result, a 200-microsecond spin-coherence time was produced. The enhanced interactions and extended spin-coherence times are essential steps toward realizing quantum computing systems to solve some problems faster than conventional systems.
Using X-rays, scientists measured the ultrafast response of DNA nucleobases to UV light. They found that the UV excited state in the nucleobase thymine decays rapidly, harmlessly dissipating the potentially destructive UV energy. The findings give new insight on how the nucleobases inside DNA protect themselves from light-induced damage.
A quantum mechanical transport phenomenon demonstrated for the first time in synthetic, atomically-thin layered material at room temperature could lead to novel nanoelectronic circuits and devices, according to researchers at Penn State and three other U.S. and international universities.
After collecting data on a leukemia-affected family for nearly a decade, Children’s Hospital of Michigan, Detroit Medical Center (DMC), Hematologist and Wayne State University School of Medicine Professor of Pediatrics Madhvi Rajpurkar, M.D., joined an international team of genetic researchers in an effort to track down a mutation partly responsible for causing the disease. Their findings, recently published in one of the world’s leading science journals, have “major implications” for better understanding the genetic basis of several types of cancer, including leukemia.
By manipulating the activity of Activin receptors in the brain, researchers were able to increase or decrease cocaine-taking and relapse behavior in animal models. The study focused on receptors in regions of the brain involved in pleasure and reward.
A team of University of Washington researchers has identified a mechanism that some plant cells use to receive complex and contradictory messages from their neighbors.
For the first time, researchers have shown that a dissociation pathway called roaming radical dynamics is a possibility for not just simple, single molecule reactions but more complex, multiple molecule, or bimolecular, reactions.
In a study that could improve the safety of next-generation batteries, researchers discovered that adding two chemicals to the electrolyte of a lithium metal battery prevents the formation of dendrites – “fingers” of lithium that pierce the barrier between the battery’s halves, causing it to short out, overheat and sometimes burst into flame.
A team of researchers led by Yu-Hua Tseng, Ph.D., Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, has created cell lines of human brown and white fat precursor cells that will help investigators to pick apart the factors that drive the development and activity of each type of cell.
A major international study finds that surprisingly few bee species are responsible for pollinating the planet's crops: only two percent of wild bee species pollinate 80 percent of bee-pollinated crops worldwide.
Researchers from the Johns Hopkins Bloomberg School of Public Health have located a new – and likely more promising, they say – target for a potential vaccine against malaria, a mosquito-borne illness that kills as many as 750,000 people each year.
They’re pesky and annoying when they get into your fruit, but Drosophila melanogaster, more affectionately known as the “fruit fly,” have led researchers at Florida Atlantic University to an unexpected discovery involving drowning and comas.
Scientists have observed, in metals for the first time, transient excitons – the primary response of free electrons to light. Detecting excitons in metals could provide clues on how light is turned into energy in solar cells and plants.
Challenging previously held views, scientific results show that californium can covalently bond with borate, dramatically altering the electronic characteristics of the californium ion. This research may show how to further optimize nuclear reactor fuel processes.
A research team has realized one of the long-standing theoretical predictions in nonlinear optical metamaterials: creation of a nonlinear material that has opposite refractive indices at the fundamental and harmonic frequencies of light.
Researchers have found the genetic ‘needles in a haystack’ to gain the first hints at how diatoms — tiny drifting algae that carry out a large part of Earth’s photosynthesis — detect and respond to increasing carbon dioxide in the world's oceans.
A research team's discovery of new information about how plants synthesize carotenoids, precursors for vitamin A that are essential for plant development and survival, and human health, could help scientists increase the levels of provitamin A in food crops and reduce global vitamin A deficiency.
A decade of work at Johns Hopkins has yielded a computer formula that predicts which mutations are likely to have the largest effect on the activity of "genetic dimmer switches," suggesting new targets for diagnosis and treatment of many complex diseases.
Led by James Hone’s group at Columbia Engineering, a team of scientists from Columbia, SNU, and KRISS demonstrated—for the first time—an on-chip visible light source using graphene, an atomically thin and perfectly crystalline form of carbon, as a filament. They attached small strips of graphene to metal electrodes, suspended the strips above the substrate, and passed a current through the filaments to cause them to heat up. (Nature Nanotechnology AOP June 15)
Chemists at The Scripps Research Institute have invented the first practical, scalable method for synthesizing jiadifenolide, a plant-derived molecule that may have powerful brain-protecting properties.
Chemists have witnessed atoms of one chemical element morph into another for the first time ever—a feat that produced an unexpected outcome that could lead to a new way to safely treat cancer with radiation.
Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore’s MinIONTM device, a genome sequencer that can fit in the palm of your hand.
Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence.
An experimental drug improves the ability of heart muscle cells damaged by heart failure to pump blood, according to the results of a study led by Icahn School of Medicine at Mount Sinai.
Scientists from the Florida campus of The Scripps Research Institute have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming cells in patients suffering from bone loss.
X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory have for the first time observed an exotic property that could warp the electronic structure of a material in a way that reduces heat buildup and improves performance in ever-smaller computer components.
An international team of scientists has found that the climatic events that ended the ice age before last are surprisingly different to those of the last ice age.
An international team of scientists has found that the climatic events that ended the ice age before last are surprisingly different to those of the last ice age.
A previously unknown link between the immune system and the death of motor neurons in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, has been discovered by scientists at the CHUM Research Centre and the University of Montreal.