DNA Chips as Storage Media of the Future: What challenges need to be overcome
Julius-Maximilians-Universität WürzburgThe hereditary molecule DNA can store a great deal of information over long periods of time in a very small space.
The hereditary molecule DNA can store a great deal of information over long periods of time in a very small space.
Cross-pollinated soybeans offer potential for researchers to introduce new crop improvements, improve farmer’s harvests and provide forage for pollinators.
Researchers have identified a way to assess brain activity in sleep that occurs in the earliest stages of Alzheimer’s disease, typically many years prior to developing symptoms of dementia.
The Gerstner Sloan Kettering Graduate School of Biomedical Sciences (GSK) at Memorial Sloan Kettering Cancer Center (MSK) today announced The Pat and Ian Cook Doctoral Program in Cancer Engineering, made possible by a generous gift of $15 million from Pat and Ian Cook.
Chemists are building nanospheres that act as super enzymes to break down the plant fibers in biomass such as crop residues. The new catalysts could make biomass a practical source of sugars that can be converted into fuels and chemicals.
Rutgers scientists have devised a highly accurate method for creating coatings of biologically active materials for a variety of medical products. Such a technique could pave the way for a new era of transdermal medication, including shot-free vaccinations, the researchers said.
Scientists recreate and compare molecular languages at the origin of life – opening new doors for the development of novel nanotechnologies.
Addressing climate change isn't just a technical issue; it's a societal one. A recent article in Nature Energy highlights the increasing urgency for engineers and social scientists to combine their expertise.
Brinter Bio-Implant company joined the RegeneratOR’s Innovation Accelerator in 2023, located in the Regenerative Medicine Hub (RegenMed Hub), a rapidly growing regenerative medicine ecosystem based in the Innovation Quarter, in Winston-Salem.
Two molecular languages at the origin of life have been successfully recreated and mathematically validated, thanks to pioneering work by Canadian scientists at Université de Montréal.
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules.
While aloe sap is in high demand, the peels are thrown away as agricultural waste. Now, scientists who have identified several bioactive compounds in extracts from the peels that deter insects report that these peels can act as a natural insecticide. They will present their results at ACS Fall 2023.
Virginia Tech researchers examined data from 2009 to 2019 from U.S. institutions with more than $40 million in National Institutes of Health funding and at least 15 utility patents. The presence of a well-funded engineering unit correlated with stronger patent production. The results are in Nature Biotechnology.
Ever since gene editing became feasible, researchers and health officials have sought tools that can quickly and reliably distinguish genetically modified organisms from those that are naturally occurring. Now, such tools exist.
Mechanisms that control “beige/brite” thermogenic adipose tissue development may be harnessed to improve human metabolic health. To define these mechanisms, we developed a species-hybrid model in which human mesenchymal progenitor cells were used to develop white or thermogenic/beige adipose tissue in mice.
Researchers at the University of Illinois Urbana-Champaign demonstrated a way to use electricity to recycle polyoxymethylene (POM), a form of plastic that’s growing in use but more challenging to recycle.
Cancer cells can evade the body’s immune defenses by exploiting a normally helpful and ubiquitous group of molecules known as mucins.
Creating new technologically advanced sensors, scientists from UC San Diego and Australia have engineered bacteria that detect the presence of tumor DNA in live organisms. Their innovation could pave the way to new biosensors capable of identifying various infections, cancers and other diseases.
Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell targeting therapies based on its proprietary Alluminox™ platform today announces an exclusive licensing and commercialization agreement with Hikma Pharmaceuticals PLC (Hikma), a multinational pharmaceutical company for the Middle East and North Africa (MENA).
Researchers from University of British Columbia and Michigan State University have invented a system that can quickly and inexpensively detect airborne viruses using the same technology that enables high-speed trains.
Researchers have successfully grown bacterial cells in potential sand-based construction materials, as detailed in a paper published by Research Directions: Biotechnology Design, a new journal from Cambridge University Press.
A remarkable breakthrough, a collaborative team of researchers has unveiled a miniature human heart model that could potentially transform drug testing and cardiovascular research.
Since its inception in 2014, Insilico Medicine has developed multiple AI models for predicting the probability of success of clinical trials focusing on Phase II to Phase III transition probabilities.
rancis Medical, Inc., a privately held medical device company developing an innovative and proprietary water vapor ablation therapy for the treatment of prostate, kidney and bladder cancer, today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Device Designation for its Vanquish minimally invasive water vapor ablation therapy.
A spinal cord injury is a life-altering event, and the effects, such as muscle weakness and paralysis, can dramatically disrupt a person’s life. While there is no cure for paralysis, there has been some progress in developing potential treatment options to improve symptoms. Still, much of it remains out of reach to many patients.
A new review paper co-authored by two Johns Hopkins pain experts suggests that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80%–90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS). The write-up was published online July 13 in The New England Journal of Medicine.
Developing disease-resistant, high-quality improved crop varieties to benefit agricultural producers and consumers may seem like a “hairy” task, but Texas A&M AgriLife Research scientists may have gotten to the root of the issue.
BACKGROUNDScar formation and loss of cutaneous appendages are the greatest challenges in cutaneous wound healing. Previous studies have indicated that antler reserve mesenchyme (RM) cells and their conditioned medium improved regenerative w
BACKGROUNDZinc (Zn) is the second most abundant trace element after Fe, present in the human body. It is frequently reported in association with cell growth and proliferation, and its deficiency is considered to be a major disease contribut
BACKGROUNDHaploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific
BACKGROUNDCurrent evidence shows that human induced pluripotent stem cells (hiPSCs) can effectively differentiate into keratinocytes (KCs), but its effect on skin burn healing has not been reported. AIMTo observe the effects of hiPSCs-deri
BACKGROUNDMesenchymal stromal cells (MSCs) are multipotent cell populations obtained from fetal and adult tissues. They share some characteristics with limb bud mesodermal cells such as differentiation potential into osteogenic, chondrogeni
Parkinson’s disease (PD), characterized by loss of nigrostriatal dopaminergic neurons, is one of the most predominant neurodegenerative diseases affecting the elderly population worldwide. The concept of stem cell therapy in managing neur
In recent years, mesenchymal stem cells (MSC) have been considered the most effective source for regenerative medicine, especially due to released soluble paracrine bioactive components and extracellular vesicles. These factors, collectivel
Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant challenges in the treatment of severe AP and contributing to increased mortality rates. Mesenchymal stem cells (MSCs) release bioactive molecules
Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.
PBD Biotech developers of Actiphage TB, a ground-breaking phage-based diagnostic for laboratory tuberculosis testing, has today announced it has secured the grant of a US patent for its diagnostic kit. The company is exhibiting in the AACC Clinical Lab Expo on booth #4578.
Researchers have created a unique microscopic toolkit of ‘green’ tuneable electrical components, paving the way for a new generation of bioelectronic devices and sensors.
A new study describes how a novel nanomaterial can treat disorders of toxic levels of hydrogen sulfide that occur in Down syndrome and many other disorders.
Base editing technology invented at Rutgers, The State University of New Jersey, and exclusively licensed to Revvity, Inc. subsidiary Horizon Discovery, has been sub-licensed to biopharmaceutical company AstraZeneca to support its creation of cell therapies for the treatment of cancer and immune-mediated diseases.
Scientists from The Federal Research Centre “Fundamentals of Biotechnology” of the Russian Academy of Sciences (Research Center of Biotechnology RAS) elaborated mathematical algorithm that enabled to find dispersed repeated elements in genome with great accuracy.
Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.
Microbes have enormous potential to produce metabolites with potential industrial applications. To do so, microbes use groups of genes called biosynthetic gene clusters (BGCs) that code for the sets of necessary enzymes. Scientists have computationally predicted the products of hundreds of thousands of BGCs, but have experimentally confirmed fewer than 2,000 of them. Researchers have now developed a computational and experimental strategy to redesign BGCs and determine the natural chemical products they create.
Microbial communities are widely used biotechnology suppliers for processes like manufacturing biofuels and new foods, or helping crops grow better.
Scientists from Research Center of Biotechnology RAS with colleagues developed a set of plasmids that deliver CRISPR-Cas9 component genes into cells in the form of individual DNA molecules that are combined into a single genetic construct directly in yeast.
In the next step toward producing the answer to kidney transplantation shortages, Dr. Anthony Atala, Director of the Wake Forest Institute for Regenerative Medicine (WFIRM), and the kidney research team, have been awarded the prestigious KidneyX Track 2 $1 Million Prize for work based on a 3D kidney construct platform.
Although early detection of osteoporosis could help physicians intervene as soon as possible, this type of detection is not yet possible with current diagnostic tests. Now researchers reporting in ACS Central Science have developed a biosensor that could help identify those at risk for osteoporosis.
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, today announced the five founding new members of the Alliance for Genomic Discovery (AGD).
Halo Labs, a pioneer in life science instrumentation, announced the launch of its new Aura®+ Subscription Program.
Urotronic, Inc., a Minnesota-based medical device company pioneering the application of its drug-coated balloon technologies for use in interventional urology, today announced the world's first commercial procedure of the Optilume BPH® Catheter System to treat benign prostatic hyperplasia (BPH) was completed by Dr. Dean Elterman, urologist at University Urology Associates, in Toronto, Canada.