Designer Peptoids Mimic Nature’s Helices
Pacific Northwest National LaboratoryPNNL researchers learn to control peptoid “handedness,” one key to precision drug delivery and diagnostics.
PNNL researchers learn to control peptoid “handedness,” one key to precision drug delivery and diagnostics.
New research from Penn Nursing’s Center for Health Outcomes and Policy Research (CHOPR) – recently published online in the journal Research in Nursing & Health – has successfully validated a new, streamlined version of the Practice Environment Scale of the Nursing Work Index (PES-NWI), originally authored in 2002 by Eileen T. Lake, PhD, RN, FAAN, Professor of Nursing, the Edith Clemmer Steinbright Professor in Gerontology, and Associate Director of CHOPR, who is also lead author on this publication.
Systems controlled by next-generation computing algorithms could give rise to better and more efficient machine learning products, a new study suggests.
University of Washington researchers created and tested a prototype browser extension called Viblio, which lets viewers and creators add citations to the timelines of YouTube videos.
UC San Diego researchers found that, during the peak of the COVID-19 pandemic, people experiencing homelessness and people who inject drugs in San Diego and Tijuana often did not have access to drinking water, toilets, handwashing and showers.
A novel study including University of California, Irvine School of Education researchers has yielded differing results on the impact of publicly funded U.S. preschool programs on student performance beyond early childhood. A study detailing the findings was published this month in Science.
Having social support and strong social networks is vital to the health and well-being of older adults living with HIV, according to a Rutgers Health study.
A group of UC San Diego researchers, centered at UC San Diego's Institute for Network Medicine, teamed up with rheumatologists at the University of Leeds in the United Kingdom to solve a medical mystery.
In a major breakthrough for the field of artificial intelligence (AI), researchers have developed a new class of organic semiconductors with narrow bandgaps that greatly improve the performance of infrared (IR) photodetectors and image arrays.
Esophageal cancer (EC) is an aggressive malignancy with a poor prognosis, with its development and progression potentially influenced by changes in the esophageal microbiome. Recent studies have revealed that specific microbiome compositions might be linked to EC's development, response to treatment, and patient prognosis.
The universe’s earliest stars, known as Population III stars, are notoriously hard to detect with even our most powerful observatories due to their great distance and short lifetime.
A recent review has unveiled revolutionary methods to recycle and transform everyday polyethylene terephthalate (PET) plastic into valuable materials. By harnessing cutting-edge enzymes and catalysts, the review dramatically improves how we break down and reuse PET, slashing energy use and emissions.
Blue light improves bladder cancer detection across races; Gamma waves distinguish goal-oriented movements; Giving abnormal bone formation a closer look; Dissecting the HIV-1 transcriptional circuitry
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.
We all know that communication encompasses so much more than words. Facial expressions, intonations, hand gestures, and more contribute to our expressiveness. However, in social media, these intricacies are lost.
New Fossil Bovids from Kromdraai shed light on South Africa's ancient ecosystems.
فينيكس — التهابات المسالك البولية التهابات شائعة لكنها قد تصبح خطيرة.
A infecção do trato urinário (ITU) é comum, mas pode ser grave. "As infecções simples do trato urinário podem ser gerenciadas pelo seu clínico geral, mas quando elas se tornam complexas, levando a outras questões ou problemas, deve-se procurar os cuidados de um especialista", explica o Dr. Mitchell Humphreys, urologista da Mayo Clinic no Arizona.
La infección del tracto urinario (ITU) es común, pero puede ser grave. "Las infecciones simples del tracto urinario pueden ser manejadas por su médico de familia, pero cuando se vuelven complejas, lo que lleva a otras cuestiones o problemas, uno debe buscar la atención de un especialista", explica el Dr. Mitchell Humphreys, urólogo de Mayo Clinic en Arizona.
With the recent ESG-inspired shift towards and away from the rationing of capital to specific firms that arguably generate negative externalities, a new study shows targeted credit rationing in recent history has been widely ineffective in promoting change.
A groundbreaking multicenter cohort study in China has illuminated the impact of sex on the outcomes of liver transplantation (LT) for hepatocellular carcinoma (HCC), the most common type of liver cancer.
The US is experiencing dual overlapping public health crises of drug poisoning (herein, drugs) and firearm deaths. Since 1999, more than 1 million residents of the US have died by fatal drug poisonings and more than 750 000 by firearms.
A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).
A new study led by the University of Portsmouth in England has developed an innovative method to customise and strengthen DNA origami structures, which could lead to advances in medicine, biotechnology, and beyond.
With the development of genome sequencing technologies, many long non-coding RNAs (lncRNAs) have been identified in fruit and vegetables.
After a century of functional extinction on the Australian mainland, a Flat oyster reef has been successfully restored along a metropolitan Adelaide coastline.
A new Lancet Oncology article describes how climate-driven risks in the Caribbean negatively affect every step in the cancer control continuum, from etiology to survivorship.
Researchers leading a national dialogue about parental burnout from The Ohio State University College of Nursing and the university’s Office of the Chief Wellness Officer found that pressure to try to be “perfect” leads to unhealthy impacts on both parents and their children.
Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
How a non-invasive technique temporarily opened the blood-brain barrier to deliver an immunotherapy drug to the brain in a large animal study.
Researchers used advanced computing techniques to engineer the bacteria Pseudomonas putida to optimize its production of isoprenol using carbon from plant material. Isoprenol has a potential role in the production of jet biofuel blendstocks.
Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors—an advance that could transform cancer treatment. The promising findings, reported today in Science Advances, involve CAR-T cell therapy, which supercharges the immune system to identify and attack cancer cells.
A study that used artificial intelligence (AI) and social media posts to assess the rates of depression and anxiety in nearly half of American counties found that the AI-generated measurements produced more reliable assessments than population surveys. The findings are published in Nature Digital Medicine.
Spina bifida is the most common structural disorder of the human nervous system. The causes are largely unknown, but University of California San Diego researchers led a study that points to a link involving a chromosomal microdeletion — and also underscores the value of folic acid as a preventive measure.
Many parents ponder why one of their children seems more emotionally troubled than the others. A new study in the United Kingdom reveals a possible basis for those differences.
The May issue of The American Journal of Gastroenterology highlights new clinical science and reviews on hepatic encephalopathy management using a smartphone app’s artificial intelligence, cyclic vomiting syndrome prevalence and incidence, alcohol-associated liver disease and alcohol use disorder in young women, and polypectomy technique.
ChatGPT, the artificial intelligence (AI) chatbot designed to assist with language-based tasks, can effectively extract data for research purposes from physicians' clinical notes, UT Southwestern Medical Center researchers report in a new study. Their findings, published in NPJ Digital Medicine, could significantly accelerate clinical research and lead to new innovations in computerized clinical decision-making aids.
Lawrence Livermore National Laboratory’s (LLNL) Space Program is now building an optical space domain awareness payload for an upcoming mission by the U.S. Space Force.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
These days, detecting a planetary atmosphere tens or even hundreds of light-years from Earth might not sound like such a big deal. Scientists have found signs of atmosphere surrounding dozens of exoplanets over the past two decades.
To validate the PECARN prediction rules, Children's Hospital Los Angeles researchers collaborated on a prospective, multicenter study funded by the National Institutes of Health, enrolling thousands of children who came to the CHLA Emergency Department over a five-year period.
In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.
Local decision-makers looking for ways to reduce the impact of heat waves on their communities have a valuable new capability at their disposal: a new study on vegetation resilience.
In a groundbreaking development for addressing future viral pandemics, a multi-institutional team involving Lawrence Livermore National Laboratory researchers has successfully combined an artificial intelligence-backed platform with supercomputing to redesign and restore the effectiveness of antibodies whose ability to fight viruses has been compromised by viral evolution. The work was published in the journal Nature.
Researchers at the Icahn School of Medicine at Mount Sinai have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to produce potential therapeutic effects in patients with neuropsychiatric disorders such as depression and anxiety.
Researchers from the University of California, Irvine have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.
When low-income entrepreneurs start their own businesses, they frequently fear failure — a well-documented phenomenon. But over time, they may also fear success, given the costs and unknowns it can bring, and this barrier to growth is under-studied and underappreciated. A new study from a Keough School of Global Affairs expert breaks new ground by explaining this fear and offers five recommendations to help entrepreneurs overcome it and move out of poverty.
Xylyx Bio, a regenerative medicine company developing innovative solutions for tissue and organ repair, today announced entry into an exclusive license agreement with Vanderbilt University for the rights to a xenogeneic cross-circulation platform that restores damaged donor organs to transplant condition.
4C Medical Technologies, Inc. ("4C Medical"), a medical device company dedicated to advancing minimally invasive therapies for structural heart disease, has been granted Breakthrough Device designation by the U.S.
Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings, recently published in Circulation, could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.